{"id":2106235,"date":"2025-10-31T05:00:00","date_gmt":"2025-10-31T09:00:00","guid":{"rendered":"https:\/\/kffhealthnews.org\/?post_type=article&#038;p=2106235"},"modified":"2025-10-31T09:10:08","modified_gmt":"2025-10-31T13:10:08","slug":"multiple-myeloma-patients-treatment-research-cuts-racial-disparities","status":"publish","type":"article","link":"https:\/\/kffhealthnews.org\/news\/article\/multiple-myeloma-patients-treatment-research-cuts-racial-disparities\/","title":{"rendered":"Better Treatments Buoy Multiple-Myeloma Patients, Bound by Research Cuts and Racial Disparities"},"content":{"rendered":"\n<p>For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms \u2014 pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination. Her primary care physician had ruled out diabetes before finally chalking up her ailments to getting older.<\/p>\n\n\n\n<aside class=\"block--sidebar alignright \">\n\t\n\n<div class=\"wp-block-kaiser-health-news-partner block--partner\">\n\t\t\t\t\t\t<a class=\"partner__image--link\" href=\"https:\/\/www.cbsnews.com\/news\/cancer-research-cuts-racial-disparities-multiple-myeloma\/\">\n\t\t\t\t<img decoding=\"async\" class=\"partner__image\" src=\"https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2022\/07\/CBS-hi-res-logo.png?w=120\" alt=\"Partner logo\" \/>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t<p class=\"partner__content\">\n\t\tThis story also ran on <a href=\"https:\/\/www.cbsnews.com\/news\/cancer-research-cuts-racial-disparities-multiple-myeloma\/\">CBS News<\/a>. It can be <a href=\"https:\/\/kffhealthnews.org\/news\/article\/multiple-myeloma-patients-treatment-research-cuts-racial-disparities\/view\/republish\/\">republished for free<\/a>.\t<\/p>\n<\/div>\n\n<\/aside>\n\n\n\n<p>But months of intense back pain eventually landed her in the emergency room, where a doctor suggested that Hunter might have multiple myeloma. Hunter\u2019s first question was, \u201cWhat is that?\u201d<\/p>\n\n\n\n<p>Multiple myeloma is a cancer that develops in bone marrow plasma cells, crowding out healthy blood cells and damaging the bones. It is one of the most common blood cancers \u2014 and the most diagnosed among African Americans. The mortality rate from multiple myeloma also is higher among African American patients than white people, with a number of studies showing that, in addition to disease biology, societal factors such as socioeconomic status and <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37917858\/\">lack of access<\/a> to health insurance or medical services delay timely diagnoses.<\/p>\n\n\n\n<p>A belated diagnosis is what happened to Hunter, a Black woman in Montgomery, Alabama. She said her primary care doctor dismissed a recommendation from her endocrinologist to refer her to a hematologist after finding high protein counts in her blood. Then, she said, he also refused to order a bone marrow biopsy after the ER doctor suggested she might have multiple myeloma. Fed up, she said, she found a new doctor, got tested, and learned she indeed had the disease.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.dana-farber.org\/find-a-doctor\/monique-a-hartley-brown\">Monique Hartley-Brown<\/a>, a multiple myeloma researcher at the <a href=\"https:\/\/www.dana-farber.org\/\">Dana-Farber Cancer Institute<\/a> in Boston, said Hunter\u2019s experience is fairly common, particularly among Black patients who live in underserved communities.<\/p>\n\n\n\n<p>\u201cOn average, patients see their primary doctor three times before being accurately diagnosed,\u201d Hartley-Brown said. \u201cThe delay from symptom onset to diagnosis is even longer for Black Americans. Meanwhile, the disease is wreaking havoc \u2014 causing fractures, severe anemia, fatigue, weight loss, kidney problems.\u201d<\/p>\n\n\n<div\n\tclass=\"wp-block block--newsletter  \"\n\tdata-type=\"kaiser-health-news\/newsletter\"\n\tdata-align=\"center\"\n\tstyle=\"\"\n>\n\t<h4 class=\"newsletter__title\">\n\t\t<a href=\"\/email\/\">\n\t\t\tEmail Sign-Up\t\t<\/a>\n\t<\/h4>\n\t<p class=\"newsletter__description\">\n\t\tSubscribe to KFF Health News&#039; free Morning Briefing.\t<\/p>\n\t\n<form\n\taction=\"\/email-signup\/\"\n\tclass=\"kaiser-hubspot-mini-signup-form\"\n\tmethod=\"post\"\n>\n\t<input type=\"hidden\" id=\"kaiser_hubspot_nonce\" name=\"kaiser_hubspot_nonce\" value=\"00b79a3908\" \/><input type=\"hidden\" name=\"_wp_http_referer\" value=\"\/wp-json\/wp\/v2\/article\/2106235\" \/>\t\t\t\t<label\n\t\tclass=\"kaiser-hubspot-mini-signup-form__label--email\"\n\t\tfor=\"kaiser-hubspot-mini-signup-form-email\"\n\t>\n\t\t<span class=\"screen-reader-text\">\n\t\t\tYour Email Address\t\t<\/span>\n\t\t<input\n\t\t\tautocomplete=\"email\"\n\t\t\tclass=\"kaiser-hubspot-mini-signup-form__input--email\"\n\t\t\tid=\"kaiser-hubspot-mini-signup-form-email\"\n\t\t\tname=\"kaiser_hubspot_email\"\n\t\t\ttype=\"email\"\n\t\t\t\t\t\t\tplaceholder=\"Your email address\"\n\t\t\t\t\t\/>\n\t<\/label>\n\t<button class=\"kaiser-hubspot-mini-signup-form__submit\">\n\t\tSign Up\t<\/button>\n<\/form>\n<\/div>\n\n\n\n<p>Black and Hispanic patients are also less likely to receive the newest therapies, according to the Multiple Myeloma Research Foundation, and, when they do, they are more likely to do so later in the course of their disease than white patients. An <a href=\"https:\/\/ashpublications.org\/bloodadvances\/article\/6\/6\/1684\/483828\/Analysis-of-racial-and-ethnic-disparities-in\">analysis published in 2022<\/a> of racial and ethnic disparities in multiple myeloma drug approval trials submitted to the FDA concluded that Black patients made up only 4% of participants despite being roughly 20% of those living with the disease.<\/p>\n\n\n\n<p>Now, even though significant progress has been made in understanding the biology of multiple myeloma and how to treat it, those racial gaps may grow larger amid <a href=\"https:\/\/www.nytimes.com\/2025\/09\/14\/magazine\/cancer-research-grants-funds-trump.html\">federal cuts to cancer research<\/a> and the <a href=\"https:\/\/www.appliedclinicaltrialsonline.com\/view\/the-impact-of-dei-ban-on-clinical-research-ecosystem\">backlash against diversity and inclusion efforts<\/a>. While few multiple myeloma experts were willing to talk on the record about the impact of the funding cutbacks, <a href=\"https:\/\/themmrf.org\/about\/executive-leadership\/michael-andreini\/\">Michael Andreini<\/a>, president and CEO of the Multiple Myeloma Research Foundation, has written that cuts to the National Institutes of Health and its National Cancer Institute <a href=\"https:\/\/kffhealthnews.org\/news\/article\/national-cancer-institute-nih-cuts-chaos-scientific-biomedical-research\/\">put future innovations<\/a> at risk.<\/p>\n\n\n\n<p>\u201cEven before these potential cuts, funding for myeloma lagged behind,\u201d <a href=\"https:\/\/themmrf.org\/mmrf-blogs\/is-progress-in-multiple-myeloma-stalling\/\">he wrote<\/a> before the cuts were finalized. \u201cThe myeloma specific budget has decreased significantly. Myeloma is almost 2% of all cancers, yet receives less than 1% of the NCI\u2019s budget.\u201d<\/p>\n\n\n\n<p>The disease is already hard to diagnose. Because multiple myeloma is <a href=\"https:\/\/www.cancer.org\/cancer\/types\/multiple-myeloma\/about\/key-statistics.html\">usually diagnosed<\/a> when a patient is over 65 (African Americans tend to be <a href=\"https:\/\/www.myeloma.org\/blog\/myeloma-facts-for-people-of-african-descent\">diagnosed five years younger<\/a>, on average), common symptoms such as lower back pain and fatigue are often chalked up to just getting older.<\/p>\n\n\n\n<p>That\u2019s what happened to Jim Washington of Charlotte, North Carolina. He was 61 when excruciating hip pain brought his regular tennis games to a sudden stop.<\/p>\n\n\n\n<p>\u201cI figured I\u2019d done something to injure myself,\u201d Washington said. \u201cBut I\u2019d been playing tennis all my life, and this pain was different from anything I\u2019d ever felt before.\u201d<\/p>\n\n\n\n<figure class=\"wp-block-image alignwide size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"3000\" height=\"2000\" src=\"https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg\" alt=\"A photo of Jim Washington teeing up a shot at a golf course.\" class=\"wp-image-2106803\" srcset=\"https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg 3000w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=150,100 150w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=500,333 500w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=768,512 768w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=1270,847 1270w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=1536,1024 1536w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=2048,1365 2048w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=770,513 770w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=840,560 840w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=720,480 720w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=570,380 570w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=370,247 370w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=270,180 270w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=170,113 170w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=100,67 100w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=120,80 120w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=1170,780 1170w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=300,200 300w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=200,134 200w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=315,210 315w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=630,420 630w, https:\/\/kffhealthnews.org\/wp-content\/uploads\/sites\/2\/2025\/10\/Myeloma_09-resized.jpg?resize=1200,800 1200w\" sizes=\"auto, (max-width: 3000px) 100vw, 3000px\" \/><figcaption class=\"wp-element-caption\">Washington is back golfing after twice undergoing treatment for multiple myeloma. With premium health insurance and a concierge doctor, he was able to benefit from the latest treatments both times.<span class=\"photo-credit\">(A.M. Stewart for KFF Health News)<\/span><\/figcaption><\/figure>\n\n\n\n<p>Washington was fortunate to have a concierge doctor and premium health insurance. In quick succession, he underwent X-rays that revealed a lesion on his spine and received a referral to an oncologist, who identified a cancerous tumor. A subsequent biopsy and blood tests confirmed he had multiple myeloma.<\/p>\n\n\n\n<p>Washington had weeks of high-dose chemotherapy, followed by what is known as an autologous stem cell transplant, which used his own stem cells to regrow healthy blood cells in his body. It was a grueling process that ultimately left him with a clean bill of health. For the next several years, his doctors monitored him closely, including conducting an annual bone marrow biopsy.<\/p>\n\n\n\n<p>Before treatment, he said, myeloma had infiltrated 60% of his blood cells. The stem cell transplant brought those levels down to zero. After about five years, however, his multiple myeloma level had crept back up to 10% and required more treatment.<\/p>\n\n\n\n<p>But Washington had closely followed the latest research and believed he had reason to be optimistic. The FDA had approved the first <a href=\"https:\/\/www.dana-farber.org\/newsroom\/news-releases\/2021\/first-fda-approval-of-car-t-cell-therapy-for-multiple-myeloma-marks-milestone-for-patients\">CAR T-cell therapy for multiple myeloma<\/a> in 2021.<\/p>\n\n\n\n<p>Hartley-Brown said the lack of Black patients in multiple myeloma drug approval trials raises concerns about whether the trial results are equally applicable to the Black population and may help explain why treatment advances have been less effective in Black patients.<\/p>\n\n\n\n<p>She cited multiple causes for the low trial participation rate, including historical distrust of the medical establishment and a lack of available clinical trials. \u201cIf you are living in an underserved or underrepresented area, the hospital or community doctor may not have clinical trials available, or that patient may have limitations getting to that location affiliated with the clinical trial,\u201d she said.<\/p>\n\n\n\n<p>Washington, a Black patient, appears to have avoided this trap, having benefited from the latest treatments both times. In January, he began six weeks of chemotherapy with a three-drug combination of Velcade, Darzalex, and dexamethasone before undergoing CAR T-cell therapy.<\/p>\n\n\n\n<p>For that, doctors collected Washington\u2019s T cells, a type of white blood cell, and genetically modified them to better recognize and destroy the cancer cells before reinfusing them into his body. He didn\u2019t require hospitalization post-transplant and could do daily blood draws at home. His energy levels were much higher than during his first treatment.<\/p>\n\n\n\n<p>\u201cI\u2019ve been in a very privileged position,\u201d Washington said. \u201cThe prognosis is very positive, and I\u2019m feeling good about where I am at this point.\u201d<\/p>\n\n\n\n<p>Hunter, too, considers herself lucky despite receiving a delayed diagnosis. After her diagnosis in January 2017, she underwent five months of immunotherapy with a three-drug combination (Revlimid, Velcade, and dexamethasone) followed by a successful stem cell transplant and two weeks in the hospital. She has been in remission since July 2017.<\/p>\n\n\n\n<p>Hunter, now a support group co-leader and patient advocate, said that stories like Washington\u2019s and her own provide hope despite the research cuts.<\/p>\n\n\n\n<p>In the eight years since her treatment, she said, she\u2019s seen the thinking around multiple myeloma \u2014 long described as a treatable but incurable disease \u2014 begin to shift as a growing subset of patients remain disease-free for many years. She said she has even met people living with the disease for 30 years.<\/p>\n\n\n\n<p>\u201cThe word \u2018cure\u2019 is now being heard,\u201d Hunter said.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although racial disparities in the diagnosis and treatment of multiple myeloma remain, Black survivors of multiple myeloma say the latest developments in treatment give them hope even as federal research cuts create a grim forecast for cancer research.<\/p>\n","protected":false},"featured_media":2106800,"template":"","meta":{"_cr_original_post":"","_cr_replace_post_id":"","_cr_replacing_post_id":"","jetpack_post_was_ever_published":false,"kff_featured_video":0,"kff_show_featured_video":false,"kff_show_mute_audio_button":false,"custom_shortlink":"\/MjEwNjIzNQ","kaiser_health_news_byline_override":"","kaiser_health_news_can_republish":true,"kaiser_health_news_featured_image_caption":"","kaiser_health_news_header_overlay_color":"","kaiser_health_news_header_theme_slug":"theme-title-overlay","kaiser_health_news_hero_image":0,"kaiser_health_news_backdrop_padding":115,"kaiser_health_news_hide_partner":false,"kaiser_health_news_kicker":"","kaiser_health_news_kicker_background_color":"","kaiser_health_news_kicker_text_color":"","kaiser_health_news_kicker_url":"","kaiser_health_news_nav_theme_slug":"compact","kaiser_health_news_nav_transparency":false,"kaiser_health_news_sharing_title":"","kaiser_health_news_show_featured_image":true,"kaiser_health_news_subheadline":"","kaiser_health_news_suppress_kicker":false,"kaiser_health_news_suppress_subheadline":false,"kaiser_health_news_update_time":"","kaiser_health_news_vertical_image":0,"kaiser_health_news_title_align_left":false,"kaiser_health_news_custom_header_image":0,"photo_byline":[],"story_update":"","update_position":"bottom","kaiser_syndication_sites":[],"apple_news_api_created_at":"2025-10-31T09:08:23Z","apple_news_api_id":"f59bdb32-ed53-4182-8fe5-969f14b34ba2","apple_news_api_modified_at":"2025-10-31T13:10:15Z","apple_news_api_revision":"AAAAAAAAAAAAAAAAAAAAAA==","apple_news_api_share_url":"https:\/\/apple.news\/A9ZvbMu1TQYKP5ZafFLNLog","apple_news_cover_media_provider":"image","apple_news_coverimage":0,"apple_news_coverimage_caption":"","apple_news_cover_video_id":0,"apple_news_cover_video_url":"","apple_news_cover_embedwebvideo_url":"","apple_news_is_hidden":"","apple_news_is_paid":"","apple_news_is_preview":"","apple_news_is_sponsored":"","apple_news_maturity_rating":"","apple_news_metadata":"\"\"","apple_news_pullquote":"","apple_news_pullquote_position":"","apple_news_slug":"","apple_news_sections":["https:\/\/news-api.apple.com\/sections\/20265c01-23d7-4d15-96e0-0691b89c3772"],"apple_news_suppress_video_url":false,"apple_news_use_image_component":false,"footnotes":""},"categories":[178379,439527200,36835],"tags":[8017,4252,20037,439524171],"primary-topic":[],"partners":[439525973],"funder":[439528750],"coauthors":[439528972],"class_list":["post-2106235","article","type-article","status-publish","has-post-thumbnail","hentry","category-health-industry","category-race-and-health","category-syndicate","tag-alabama","tag-cancer","tag-north-carolina","tag-trump-administration","partners-cbs-news","funder-robert-wood-johnson-foundation"],"apple_news_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - 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